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VICRIVIROC MALEATE

Product Name
VICRIVIROC MALEATE
CAS No.
599179-03-0
Chemical Name
VICRIVIROC MALEATE
Synonyms
SCH-D;CS-1868;Unii-ep3qg127N9;SCH-D (maleate);SCH-417690; SCH-D;VICRIVIROC MALEATE;SCH-417690 (maleate);vicriviroc Maleate salt;VICRIVIROC MALEATE: SCH-D;Vicriviroc Malate(maleate)
CBNumber
CB01011681
Molecular Formula
C32H42F3N5O6
Formula Weight
649.7009896
MOL File
599179-03-0.mol
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VICRIVIROC MALEATE Property

storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (76.96 mM; Need ultrasonic)H2O : 25 mg/mL (38.48 mM; Need ultrasonic and warming)
form 
Powder
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H373May cause damage to organs through prolonged or repeated exposure

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML2768
Product name
Vicriviroc Maleate
Purity
≥98% (HPLC)
Packaging
1MG
Price
$94.2
Updated
2024/03/01
Sigma-Aldrich
Product number
SML2768
Product name
Vicriviroc Maleate
Purity
≥98% (HPLC)
Packaging
5MG
Price
$381
Updated
2024/03/01
Cayman Chemical
Product number
28453
Product name
Vicriviroc (maleate)
Packaging
1mg
Price
$86
Updated
2024/03/01
Cayman Chemical
Product number
28453
Product name
Vicriviroc (maleate)
Packaging
10mg
Price
$421
Updated
2024/03/01
Cayman Chemical
Product number
28453
Product name
Vicriviroc (maleate)
Packaging
5mg
Price
$274
Updated
2024/03/01
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VICRIVIROC MALEATE Chemical Properties,Usage,Production

Description

Vicriviroc is a chemokine (C-C motif) receptor 5 (CCR5) antagonist (Ki = 2.5 nM). It selectively inhibits CCR5 over M1 and M2 muscarinic acetylcholine receptors (Kis = >10,000 nM for both) and human-ether-a-go-go (hERG) potassium channels (IC50 = 5.8 μM). Vicriviroc decreases chemotaxis induced by chemokine (C-C motif) ligand 3 (CCL3) in Ba/F3 cells expressing recombinant human CCR5 with an IC50 value of 0.91 nM. It inhibits the replication of 30 R5-tropic HIV-1 clinical isolates in peripheral blood mononuclear cells (PBMCs; EC50s = 0.04-1.4 nM) and reduces viral entry of seven drug-resistant strains of HIV-1 in U87 cells expressing CD4 and CCR5 (EC50s = 8.7-32.9 nM).

Uses

Antiviral, CCR5 antagonist, treatment of autoimmune conditions.

VICRIVIROC MALEATE Preparation Products And Raw materials

Raw materials

Preparation Products

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VICRIVIROC MALEATE Suppliers

China 40 India 1 United Kingdom 1 United States 14 Global 56
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View Lastest Price from VICRIVIROC MALEATE manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Vicriviroc maleate 599179-03-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Vicriviroc maleate 599179-03-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

599179-03-0, VICRIVIROC MALEATERelated Search:

Dioctadecyl dimethyl ammonium chloride 2,6-Lutidine 2-Amino-4,6-dimethylpyrimidine Vicriviroc Malate (4,6-dimethylpyrimidin-5-yl)-[4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluor omethyl)phenyl]ethyl]-3-methyl-piperazin-1-yl]-4-methyl-1-piperidyl]me thanone Vicriviroc (hydrochloride)

  • SCH-417690; SCH-D
  • CS-1868
  • Vicriviroc Malate(maleate)
  • Vicriviroc Maleate(SCH 417690)
  • (4,6-diMethylpyriMidin-5-yl)(4-((S)-4-((R)-2-Methoxy-1-(4-(trifluoroMethyl)phenyl)ethyl)-3-Methylpiperazin-1-yl)-4-Methylpiperidin-1-yl)Methanone fuMarate
  • vicriviroc Maleate salt
  • 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate VicrivirocMalate
  • Vicriviroc maleate 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate
  • SCH-D
  • VICRIVIROC MALEATE
  • VICRIVIROC MALEATE: SCH-D
  • Unii-ep3qg127N9
  • 1-[(4,6-Dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methylpiperidine (2Z)-2-butenedioate
  • (4,6-dimethylpyrimidin-5-yl)(4-((S)-4-((R)-2-methoxy-1-(4-(trifluoromethyl)phenyl)ethyl)-3-methylpiperazin-1-yl)-4-methylpiperidin-1-yl)methanone maleate
  • SCH-417690 (maleate)
  • SCH-D (maleate)
  • Vicriviroc maleate (SCH-417690 maleate）
  • Piperidine, 1-[(4,6-dimethyl-5-pyrimidinyl)carbonyl]-4-[(3S)-4-[(1R)-2-methoxy-1-[4-(trifluoromethyl)phenyl]ethyl]-3-methyl-1-piperazinyl]-4-methyl-, (2Z)-2-butenedioate (1:1) (9CI, ACI)
  • SCH-D,CCR,Inhibitor,HIV,CC chemokine receptor,SCH417690,inhibit,Vicriviroc maleate,SCH-417690,Vicriviroc,Human immunodeficiency virus,SCH 417690
  • 599179-03-0
  • C28H38F3N5O2C4H4O4
  • C4H4O4C28H38F3N5O2
  • C32H42F3N5O6